影像学定量评估腰椎间盘退变的研究进展

被引：6

作者：

张刚 ^{[1
]}

陈健 ^{[1
]}

常俊 ^{[2
]}

陈洁 ^{[1
]}

刘玲玲 ^{[1
]}

张忠正 ^{[1
]}

李兆龙 ^{[3
]}

机构：

[1] 安徽医科大学第一附属医院/安徽省公共卫生临床中心康复医学科

[2] 安徽医科大学第一附属医院/安徽省公共卫生临床中心骨科

[3] 安徽医科大学第一附属医院/安徽省公共卫生临床中心放射科

来源：

中国脊柱脊髓杂志 | 2024年 / 34卷 / 07期

基金：

安徽省自然科学基金;

关键词：

D O I：

暂无

中图分类号：

R445 [影像诊断学]; R681.53 [];

学科分类号：

100231 [临床病理学];

摘要：

<正>腰痛是临床上最为常见的疾患之一，常反复发作，严重影响患者的生活质量[1]。椎间盘退变（intervertebral disc degeneration,IDD）是引起腰痛最常见的病因[1～3]。IDD在早期干预治疗效果最佳，当椎间盘退变程度较重时，椎间盘修复的可能性极低[2、4]。常规影像学检查难以对IDD早期进行检测和定量评估[4～6]。在一些关于IDD再生修复治疗的新手段的临床研究中，多以患者的疼痛改善、椎旁肌肉肌电信号、椎间盘高度、髓核视觉信号改变等作为疗效评估指标[2、7]。这些指标无法直接定量反映退变椎间盘内细胞外基质的增减，难以准确客观地说明退变椎间盘的再生修复情况。因此，早期诊断和定量评估IDD的意义重大。

引用

页码：769 / 773

页数：5

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