增龄性骨骼肌减少症诊断与干预的研究现状

被引：22

作者：

方磊

刘玉超

机构：

[1] 上海中医药大学附属岳阳中西医结合医院推拿科

来源：

中国组织工程研究与临床康复 | 2009年 / 13卷 / 02期

关键词：

增龄性骨骼肌减少症; 诊断; 干预方法; 综述;

D O I：

暂无

中图分类号：

R685 [肌肉疾病及损伤];

学科分类号：

100220 [骨科学];

摘要：

增龄性骨骼肌减少症的发生与增龄性肌纤维丧失,体力活动的减少,激素水平的下降,营养缺乏等密切相关,在诊断方面没有统一的标准,目前公认的诊断方法包括伸膝等长力矩、相对骨骼肌指数、无脂体重、肌电图、步态分析、握力、下肢肌力、磁共振成像和B超检测等。治疗上通过调节饮食、替代给药、抗阻训练改善增龄性骨骼肌减少症患者神经肌肉功能逐渐减退的情况,防止卫星细胞的脂肪化,提高生长激素-胰岛素样生长因子1轴的活力。今后在治疗方面可掺合中医特色疗法到抗阻练习和营养方法中或组合激素和营养干预,设计正交试验找出最优交互作用的干预组合,以及进行随访观察疗法的长期安全性和有效性等。

引用

页码：392 / 395

页数：4

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