我国手足口病病原谱以及疫苗研究新动态

被引：22

作者：

毛群颖

卞莲莲

王一平

梁争论

机构：

[1] 中国食品药品检定研究院

来源：

中国生物制品学杂志 | 2015年 / 28卷 / 09期

关键词：

手足口病; 病原谱; 肠道病毒; 疫苗;

D O I：

10.13200/j.cnki.cjb.001041

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

手足口病(hand,foot and mouth disease,HFMD)已成为西太区国家和我国的严重公共卫生问题,研发疫苗为控制HFMD暴发的有效措施。目前,我国首创的EV71疫苗已完成Ⅲ期临床试验,有望在年内上市,CA16疫苗以及EV71/CA16联合疫苗的临床前研究也已取得进展。但近年来,HFMD病原谱的改变以及易引起重症病例的CB组在HFMD中检出率上升的报道,对HFMD的防控提出了新的挑战。本文对HFMD病原谱和相关疫苗的研究进展作一综述,并提出研发多价疫苗防控严重HFMD的必要性。

引用

页码：979 / 984

页数：6

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