骨髓间充质干细胞向神经元样细胞分化及其在神经修复中的应用

被引:4
作者
袁章 [1 ]
杨拯 [2 ]
徐艳 [2 ]
张晓 [2 ]
机构
[1] 成都医学院临床医学系
[2] 成都医学院基础医学院
关键词
BMSCs; 小鼠; 转分化; 小家鼠; 神经元样细胞; 骨髓间充质干细胞; 神经修复;
D O I
暂无
中图分类号
R329 [人体组织学]; R651 [头部及神经外科学];
学科分类号
摘要
<正>近几年来,干细胞已成为生物学和医学领域的研究热点。间充质干细胞来源于中胚层,具有很强的自我更新、增殖能力以及多向分化的潜能。而骨髓间充质干细胞(bone
引用
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页码:766 / 769
页数:4
相关论文
共 16 条
[1]   骨髓间质干细胞经静脉注射移植对大鼠脊髓损伤后BDNF、NGFmRNA表达的影响 [J].
董锋 ;
林建华 ;
吴朝阳 .
中国康复医学杂志, 2008, (05) :416-419
[2]  
Transdifferentiation of bone marrow stromal cells into Schwann cell phenotype using progesterone as inducer[J] . Bahar Movaghar,Taki Tiraihi,Seyed A. Mesbah-Namin.Brain Research . 2008
[3]   Bone marrow stromal cells can be delivered to the site of traumatic brain injury via intrathecal transplantation in rabbits [J].
Liu, Wenpeng ;
Jiang, Xiaodan ;
Fu, Xiafei ;
Cui, Shaojie ;
Du, Mouxuan ;
Cai, Yingqian ;
Xu, Ruxiang .
NEUROSCIENCE LETTERS, 2008, 434 (02) :160-164
[4]   Neurotrophic Schwann-cell factors induce neural differentiation of bone marrow stromal cells [J].
Zurita, Mercedes ;
Vaquero, Jesus ;
Oya, Santiago ;
Bonilla, Celia ;
Aguayo, Concepcion .
NEUROREPORT, 2007, 18 (16) :1713-1717
[5]   Neurotrophic and growth factor gene expression profiling of mouse bone marrow stromal cells induced by ischemic brain extracts [J].
Qu, Runjiang ;
Li, Yi ;
Gao, Qi ;
Shen, Lihong ;
Zhang, Jing ;
Liu, Zhongwu ;
Chen, Xiaoguang ;
Chopp, Michael .
NEUROPATHOLOGY, 2007, 27 (04) :355-363
[6]   Culture and neural differentiation of rat bone marrow mesenchymal stem cells in vitro [J].
Zhao Lei ;
Lin Yongda ;
Ma Jun ;
Sun Yingyu ;
Zeng Shaoju ;
Zhang Xinwen ;
Zuo Mingxue .
CELL BIOLOGY INTERNATIONAL, 2007, 31 (09) :916-923
[7]  
Role of SDF-1/CXCR4 system in survival and migration of bone marrow stromal cells after transplantation into mice cerebral infarct[J] . Hideo Shichinohe,Satoshi Kuroda,Shunsuke Yano,Kazutoshi Hida,Yoshinobu Iwasaki.Brain Research . 2007
[8]   Peripheral nerve regeneration by the in vitro differentiated-human bone marrow stromal cells with Schwann cell property [J].
Shimizu, Satoshi ;
Kitada, Masaaki ;
Ishikawa, Hiroto ;
Itokazu, Yutaka ;
Wakao, Shohei ;
Dezawa, Mari .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2007, 359 (04) :915-920
[9]   Basic fibroblast growth factor promotes bone marrow stromal cell transplantation-mediated neural regeneration in traumatic brain injury [J].
Bhang, Suk Ho ;
Lee, Young Eun ;
Cho, Seung-Woo ;
Shim, Jae-Won ;
Lee, Sang-Hun ;
Choi, Cha Yong ;
Chang, Jin Woo ;
Kim, Byung-Soo .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2007, 359 (01) :40-45
[10]  
Bone marrow stromal cells stimulate neurite outgrowth over neural proteoglycans (CSPG), myelin associated glycoprotein and Nogo-A[J] . Karina T. Wright,Wagih El Masri,Aheed Osman,Sally Roberts,Giselle Chamberlain,Brian A. Ashton,William E.B. Johnson.Biochemical and Biophysical Research Communications . 2007 (2)