肠道菌群与炎症性肠病的研究进展

被引：22

作者：

彭帅

沈磊

机构：

[1] 武汉大学人民医院消化内科

来源：

医学综述 | 2019年 / 25卷 / 16期

关键词：

炎症性肠病; 肠道菌群; 溃疡性结肠炎; 菌群失调;

D O I：

暂无

中图分类号：

R574 [肠疾病];

学科分类号：

100201 [内科学];

摘要：

炎症性肠病(IBD)被认为是一种非特异性的慢性复发性肠道炎症疾病,多认为是由遗传因素、环境因素、肠道菌群和宿主免疫系统等的复杂相互作用导致的异常免疫反应和慢性肠道炎症,但确切病因和发病机制尚未完全阐明。正常肠道微生物群可形成生物屏障,起到促消化、营养吸收、免疫、抗肿瘤以及代谢等作用,对宿主的健康有益。新一代测序技术的最新进展已经确定了IBD中肠道微生物群的组成和功能的改变,这些改变可能与IBD发生有关。因此,探索和运用血清学微生物标志诊断IBD成为可能,也为IBD治疗方案提供了全新方法。

引用

页码：3141 / 3145+3150 +3150

页数：6

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