Bioactive natural products derived from the Central African flora against neglected tropical diseases and HIV

被引：60

作者：

Zofou, Denis ^{[1
]}

Ntie-Kang, Fidele ^{[2
,3
]}

Sippl, Wolfgang ^{[4
]}

Efange, Simon M. N. ^{[2
]}

机构：

[1] Univ Buea, Biotechnol Unit, Dept Biochem & Mol Biol, Buea, Cameroon

[2] Univ Buea, Dept Chem, Chem & Bioact Informat Ctr, Buea, Cameroon

[3] Univ Douala, Fac Sci, CEPAMOQ, Douala, Cameroon

[4] Univ Halle Wittenberg, Dept Pharmaceut Sci, D-06120 Halle, Saale, Germany

来源：

NATURAL PRODUCT REPORTS | 2013年 / 30卷 / 08期

关键词：

BIOASSAY-GUIDED FRACTIONATION; VITRO ANTIPLASMODIAL ACTIVITY; FUROQUINOLINE ALKALOIDS; NAPHTHYLISOQUINOLINE ALKALOIDS; MEDICINAL-PLANTS; ROOT BARK; STEM BARK; ANTIMALARIAL COMPOUNDS; PLASMODIUM-FALCIPARUM; ACTIVE CONSTITUENT;

D O I：

10.1039/c3np70030e

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This review discusses the medicinal potential of bioactive metabolites isolated from medicinal plants in Central Africa for the treatment of neglected tropical diseases and HIV. A correlation is established between the biological activities of the isolated compounds and the uses of the plants in traditional medicine. Insight is provided on how secondary metabolites from medicinal plants in Central Africa could be exploited for drug discovery.

引用

页码：1098 / 1120

页数：23

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