Strained azetidinium ylides: New reagents for cyclopropanation

被引：52

作者：

Couty, Francois ^{[1
]}

David, Olivier ^{[1
]}

Larmanjat, Benedicte ^{[1
]}

Marrot, Jerome ^{[1
]}

机构：

[1] Univ Versailles St Quentin En Yvelines, Inst Lavoisier, F-78035 Versailles, France

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2007年 / 72卷 / 03期

关键词：

D O I：

10.1021/jo062221e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Azetidinium ylides showed a remarkable ability to perform the cyclopropanation of Michael acceptors. Ephedrine-derived azetidinium ylides allowed the formation of substituted cyclopropanes in good yields and at a high level of stereoselectivity. The determination of the relative stereochemistries in the produced cyclopropanes gave some insight into the reaction mechanism.

引用

页码：1058 / 1061

页数：4

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