Synthesis and antitumoral activities of marine ent-chromazonarol and related compounds

被引：64

作者：

Barrero, AF ^{[1
]}

Alvarez-Manzaneda, EJ ^{[1
]}

Herrador, MM ^{[1
]}

Chahboun, R ^{[1
]}

Galera, P ^{[1
]}

机构：

[1] Univ Granada, Fac Ciencias, Dept Quim Organ, Inst Biotecnol, E-18071 Granada, Spain

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1999年 / 9卷 / 16期

关键词：

D O I：

10.1016/S0960-894X(99)00382-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Efficient syntheses of ent-isozonarol (6a), ent-isozonarone (7a) and ent-chromazonarol (8) from (-)-sclareol (12) are described. 6a and 7a show a significative antitumoral activity. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：2325 / 2328

页数：4

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