Synthesis of wiedendiol-A and wiedendiol-B from labdane diterpenes

被引：62

作者：

Barrero, AF ^{[1
]}

Alvarez-Manzaneda, EJ ^{[1
]}

Chahboun, R ^{[1
]}

机构：

[1] Univ Granada, Fac Ciencias, Dept Quim Organ, E-18071 Granada, Spain

来源：

TETRAHEDRON | 1998年 / 54卷 / 21期

关键词：

D O I：

10.1016/S0040-4020(98)00235-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two efficient enantiospecific syntheses of wiedendiol-A (1) from (-)-sclareol (7), via 11-bromo-8-drimene (11) and 8-drimen-11-al (3), are reported. The first enantiospecific synthesis of wiedendiol-B (2), via 8S,9S-driman-11-al (26), by two alternative routes starting from 7 and (+)-cis-abienol (8) is also described. 21 prepared from protocatechualdehyde (17) was used as aromatic synthon for preparing 1 and 2. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：5635 / 5650

页数：16

共 17 条

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