Genome dynamics during experimental evolution

被引：450

作者：

Barrick, Jeffrey E. ^{[1
,2
]}

Lenski, Richard E. ^{[2
,3
]}

机构：

[1] Univ Texas Austin, Dept Mol Biosci, Inst Cellular & Mol Biol, Austin, TX 78712 USA

[2] Michigan State Univ, BEACON Ctr Study Evolut Act, E Lansing, MI 48824 USA

[3] Michigan State Univ, Dept Microbiol & Mol Genet, E Lansing, MI 48824 USA

来源：

NATURE REVIEWS GENETICS | 2013年 / 14卷 / 12期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

LONG-TERM EXPERIMENT; ESCHERICHIA-COLI K-12; SPONTANEOUS MUTATION ACCUMULATION; BENEFICIAL MUTATIONS; CLONAL INTERFERENCE; ASEXUAL POPULATIONS; KEY INNOVATION; DROSOPHILA-MELANOGASTER; BACTERIAL POPULATION; MOLECULAR-SPECTRUM;

D O I：

10.1038/nrg3564

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Evolutionary changes in organismal traits may occur either gradually or suddenly. However, until recently, there has been little direct information about how phenotypic changes are related to the rate and the nature of the underlying genotypic changes. Technological advances that facilitate whole-genome and whole-population sequencing, coupled with experiments that 'watch' evolution in action, have brought new precision to and insights into studies of mutation rates and genome evolution. In this Review, we discuss the evolutionary forces and ecological processes that govern genome dynamics in various laboratory systems in the context of relevant population genetic theory, and we relate these findings to evolution in natural populations.

引用

页码：827 / 839

页数：13

共 107 条

[11] Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli [J].

Blount, Zachary D. ;

Borland, Christina Z. ;

Lenski, Richard E. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (23) :7899-7906

[12] Genomic analysis of a key innovation in an experimental Escherichia coli population [J].

Blount, Zachary D. ;

Barrick, Jeffrey E. ;

Davidson, Carla J. ;

Lenski, Richard E. .

NATURE, 2012, 489 (7417) :513-+

[13] Whole-Genome Sequencing and Phenotypic Analysis of Bacillus subtilis Mutants following Evolution under Conditions of Relaxed Selection for Sporulation [J].

Brown, Christopher T. ;

Fishwick, Laura K. ;

Chokshi, Binna M. ;

Cuff, Marissa A. ;

Jackson, Jay M. ;

Oglesby, Travis ;

Rioux, Alison T. ;

Rodriguez, Enrique ;

Stupp, Gregory S. ;

Trupp, Austin H. ;

Woollcombe-Clarke, James S. ;

Wright, Tracy N. ;

Zaragoza, William J. ;

Drew, Jennifer C. ;

Triplett, Eric W. ;

Nicholson, Wayne L. .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2011, 77 (19) :6867-6877

[14] Experimental evolution yields hundreds of mutations in a functional viral genome [J].

Bull, JJ ;

Badgett, MR ;

Rokyta, D ;

Molineux, IJ .

JOURNAL OF MOLECULAR EVOLUTION, 2003, 57 (03) :241-248

[15]

Bull JJ, 1997, GENETICS, V147, P1497

[16] Genome-wide analysis of a long-term evolution experiment with Drosophila [J].

Burke, Molly K. ;

Dunham, Joseph P. ;

Shahrestani, Parvin ;

Thornton, Kevin R. ;

Rose, Michael R. ;

Long, Anthony D. .

NATURE, 2010, 467 (7315) :587-U111

[17] Evolution after Introduction of a Novel Metabolic Pathway Consistently Leads to Restoration of Wild-Type Physiology [J].

Carroll, Sean Michael ;

Marx, Christopher J. .

PLOS GENETICS, 2013, 9 (04)

[18] Diminishing Returns Epistasis Among Beneficial Mutations Decelerates Adaptation [J].

Chou, Hsin-Hung ;

Chiu, Hsuan-Chao ;

Delaney, Nigel F. ;

Segre, Daniel ;

Marx, Christopher J. .

SCIENCE, 2011, 332 (6034) :1190-1192

[19] Microbial laboratory evolution in the era of genome-scale science [J].

Conrad, Tom M. ;

Lewis, Nathan E. ;

Palsson, Bernhard O. .

MOLECULAR SYSTEMS BIOLOGY, 2011, 7

[20] Recombination speeds adaptation by reducing competition between beneficial mutations in populations of Escherichia coli [J].

Cooper, Tim F. .

PLOS BIOLOGY, 2007, 5 (09) :1899-1905

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