Luminescent G-quadruplex Probes

被引：41

作者：

Ma, Dik-Lung ^{[1
]}

Chan, Daniel Shiu-Hin ^{[1
]}

Yang, Hui ^{[1
]}

He, Hong-Zhang ^{[1
]}

Leung, Chung-Hang ^{[2
,3
]}

机构：

[1] Hong Kong Baptist Univ, Dept Chem, Hong Kong, Hong Kong, Peoples R China

[2] Univ Macau, State Key Lab Qual Res Chinese Med, Macau, Peoples R China

[3] Univ Macau, Inst Chinese Med Sci, Macau, Peoples R China

来源：

CURRENT PHARMACEUTICAL DESIGN | 2012年 / 18卷 / 14期

关键词：

G-quadruplex; DNA; small molecules; luminescent probes; detection; INTRAMOLECULAR G-QUADRUPLEX; INTERCALATOR DISPLACEMENT ASSAY; HIGH-AFFINITY BINDING; C-DI-GMP; FLUORESCENT-PROBES; HUMAN TELOMERES; LABEL-FREE; ETHIDIUM DERIVATIVES; PROMOTER REGION; DNA STRUCTURES;

D O I：

10.2174/138161212799958314

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

G-quadruplexes have found increasing potential in applications such as molecular therapeutics, diagnostics, and sensing. As a consequence, small molecules capable of selectively detecting G-quadruplexes have received significant attention in recent literature. Our review here addresses representative advances in the development of luminescent G-quadruplex probes and highlights their potential applications in sensing and imaging.

引用

页码：2058 / 2075

页数：18

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