Detection of Carbapenemase Producers in Enterobacteriaceae by Use of a Novel Screening Medium

被引：98

作者：

Nordmann, Patrice ^{[1
]}

Girlich, Delphine ^{[1
]}

Poirel, Laurent ^{[1
]}

机构：

[1] Hop Bicetre, AP HP, Serv Bacteriol Virol,Fac Med Paris Sud, INSERM Emerging Resistance Antibiot U914, K Bicetre, France

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2012年 / 50卷 / 08期

关键词：

LACTAMASE-PRODUCING ENTEROBACTERIACEAE; KLEBSIELLA-PNEUMONIAE; BETA-LACTAMASE; RESISTANT KLEBSIELLA; ESCHERICHIA-COLI; ERTAPENEM; EXPRESSION; SPREAD; SPP;

D O I：

10.1128/JCM.06477-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A Drigalski agar-based culture medium containing an ertapenem, cloxacillin, and zinc sulfate (Supercarba medium) was tested for screening carbapenemase-producing members of the family Enterobacteriaceae. OXA-48 (n = 44), NDM (n = 25), VIM or IMP (n = 27), and KPC producers (n = 18) were detected with a low detection limit. Its overall sensitivity (95.6%) was higher than those of the currently available ChromID ESBL (bioMerieux) and CHROMagar KPC (CHROMagar) screening media. The Supercarba medium provides a significant improvement for detection of the most common types of carbapenemase producers.

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收藏

页码：2761 / 2766

页数：6

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