T cell memory

被引:443
作者
Sprent, J [1 ]
Surh, CD [1 ]
机构
[1] Scripps Res Inst, Dept Immunol, La Jolla, CA 92037 USA
关键词
T cells; memory; activation; survival; homeostasis; IL-15; IFN-1;
D O I
10.1146/annurev.immunol.20.100101.151926
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Typical immune responses lead to prominent clonal expansion of antigen-specific T and B cells followed by differentiation into effector cells. Most effector cells die at the end of the immune response but some of these cells survive and form long-lived memory cells. The factors controlling the formation and survival of memory T cells are reviewed.
引用
收藏
页码:551 / 579
页数:29
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