Palladium-catalyzed ring-forming reactions: Methods and applications

被引：72

作者：

Lautens, M ^{[1
]}

Alberico, D ^{[1
]}

Bressy, C ^{[1
]}

Fang, YQ ^{[1
]}

Mariampillai, B ^{[1
]}

Wilhelm, T ^{[1
]}

机构：

[1] Univ Toronto, Dept Chem, Davenport Labs, Toronto, ON M5S 3H6, Canada

来源：

PURE AND APPLIED CHEMISTRY | 2006年 / 78卷 / 02期

关键词：

palladium; tandem reactions; cyclization; coupling; indole; heterocycles; direct arylation;

D O I：

10.1351/pac200678020351

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Several Pd-catalyzed cyclization methods were developed, including norbornene-mediated Catellani-type reactions, a Pd-catalyzed coupling reaction of aryl iodides and allyl moieties, and a tandem C-N/C-C coupling of gem-dihalovinyl systems. These ring-forming methods were applied to the synthesis of highly functionalized carbocyclic and heterocyclic compounds. Intermolecular Pd-catalyzed methods for synthesis of highly substituted arene compounds were also developed.

引用

页码：351 / 361

页数：11

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