Colloidal Ordered Assemblies in a Polymer Shell-A Novel Type of Magnetic Nanobeads for Theranostic Applications

被引：51

作者：

Bigall, Nadja C. ^{[1
]}

Wilhelm, Claire ^{[2
]}

Beoutis, Marie-Lys ^{[2
]}

Garcia-Hernandez, Mar ^{[3
]}

Khan, Abid A. ^{[4
]}

Giannini, Cinzia ^{[6
]}

Sanchez-Ferrer, Antoni ^{[7
]}

Mezzenga, Raffaele ^{[7
]}

Materia, Maria Elena ^{[1
]}

Garcia, Miguel A. ^{[8
,9
]}

Gazeau, Florence ^{[2
]}

Bittner, Alexander M. ^{[4
,5
]}

Manna, Liberato ^{[1
]}

Pellegrino, Teresa ^{[1
,10
]}

机构：

[1] Ist Italiano Tecnol, I-16163 Genoa, Italy

[2] Univ Paris Diderot, CNRS, UMR7057, Lab MSC, F-75205 Paris 13, France

[3] CSIC, Inst Ciencia Mat Madrid, E-28049 Madrid, Spain

[4] CIC NanoGUNE Consolider Donostia, E-20018 San Sebastian, Spain

[5] Ikerbasque, Bilbao 48011, Spain

[6] CNR, Ist Cristallog, I-70126 Bari, Italy

[7] ETH, Inst Food Nutr & Hlth, CH-8092 Zurich, Switzerland

[8] CSIC, Inst Ceram & Consejo Vidrio, E-28049 Madrid, Spain

[9] IMDEA Nanociencia, E-28049 Madrid, Spain

[10] CNR, NNL, Nanosci Inst, I-73100 Lecce, Italy

来源：

CHEMISTRY OF MATERIALS | 2013年 / 25卷 / 07期

基金：

欧洲研究理事会;

关键词：

colloidal assemblies; polymer shell; MRI contrast agents; magnetic nanoparticles; CUBIC LATTICE SYSTEMS; INTERPARTICLE INTERACTIONS; HYDROPHOBIC NANOCRYSTALS; ELASTIC-SCATTERING; NANOPARTICLES; FLUORESCENT; RELAXIVITY; PARTICLES; AGENTS; SIZE;

D O I：

10.1021/cm3036746

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

We present the synthesis of polymer embedded colloidal ordered assemblies, built from highly ordered superparamagnetic manganese iron oxide nanocrystals. Each assembly is wrapped into a thin polymer shell. In-depth characterization of the nanoparticles by TEM, SAXS, SQUID, and magnetophoresis indicates that these colloidal hybrids exhibit high mobilities in external magnetic fields, and that they could efficiently serve as contrast enhancers in magnetic resonance imaging.

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页码：1055 / 1062

页数：8

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