Real-time, high velocity-resolution color Doppler optical coherence tomography

被引：79

作者：

Westphal, V ^{[1
]}

Yazdanfar, S

Rollins, AM

Izatt, JA

机构：

[1] Case Western Reserve Univ, Dept Biomed Engn, Cleveland, OH 44106 USA

[2] Case Western Reserve Univ, Dept Med, Cleveland, OH 44106 USA

来源：

OPTICS LETTERS | 2002年 / 27卷 / 01期

关键词：

D O I：

10.1364/OL.27.000034

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Color Doppler optical coherence tomography (CDOCT) is a noninvasive optical imaging technique for micrometer-scale physiological flow mapping simultaneously with morphological optical coherence tomography imaging. We have developed a novel CDOCT signal-processing strategy capable of imaging physiological flow rates at 8 frames/s. Our new strategy features hardware-implemented digital autocorrelation across subsequent scans, permitting us to measure 300-Hz-8-kHz Doppler shifts upon signals of 0.6-MHz bandwidth. The performance of the CDOCT system was demonstrated in a flow phantom and in vivo in Xenopus laevis. (C) 2002 Optical Society of America.

引用

页码：34 / 36

页数：3

共 12 条

[1] Optical Doppler tomography [J].

Chen, ZP ;

Zhao, YH ;

Srinivas, SM ;

Nelson, JS ;

Prakash, N ;

Frostig, RD .

IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS, 1999, 5 (04) :1134-1142

[2] Noninvasive imaging of in vivo blood flow velocity using optical Doppler tomography [J].

Chen, ZP ;

Milner, TE ;

Srinivas, S ;

Wang, XJ ;

Malekafzali, A ;

vanGemert, MJC ;

Nelson, JS .

OPTICS LETTERS, 1997, 22 (14) :1119-1121

[3] In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomograghy [J].

Izatt, JA ;

Kulkami, MD ;

Yazdanfar, S ;

Barton, JK ;

Welch, AJ .

OPTICS LETTERS, 1997, 22 (18) :1439-1441

[4] Optimal interferometer designs for optical coherence tomography [J].

Rollins, AM ;

Izatt, JA .

OPTICS LETTERS, 1999, 24 (21) :1484-1486

[5] Real time color Doppler optical coherence tomography using an autocorrelation technique [J].

Rollins, AM ;

Yazdanfar, S ;

Ung-arunyawee, R ;

Izatt, JA .

COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICAL SCIENCE AND CLINICAL APPLICATIONS III, PROCEEDINGS OF, 1999, 3598 :168-176

[6] In vivo video rate optical coherence tomography [J].

Rollins, AM ;

Kulkarni, MD ;

Yazdanfar, S ;

Ung-arunyawee, R ;

Izatt, JA .

OPTICS EXPRESS, 1998, 3 (06) :219-229

[7]

ROLLINS AM, IN PRESS J BIOMED OP

[8]

WESTPHAL V, 2001, P SOC PHOTO-OPT INS, V4521, P188

[9] Imaging and velocimetry of the human retinal circulation with color Doppler optical coherence tomography [J].

Yazdanfar, S ;

Rollins, AM ;

Izatt, JA .

OPTICS LETTERS, 2000, 25 (19) :1448-1450

[10] Ultrahigh velocity resolution imaging of the microcirculation in vivo using color Doppler optical coherence tomography [J].

Yazdanfar, S ;

Rollins, AM ;

Izatt, JA .

COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICAL SCIENCE AND CLINICA APPLICATIONS V, 2001, 4251 :156-164

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