The use of a micropump based on capillary and evaporation effects in a microfluidic flow injection chemiluminescence system

被引:56
作者
Guan, YX
Xu, ZR
Dai, J
Fang, ZL
机构
[1] Northeastern Univ, Res Ctr Analyt Sci, Shenyang 110004, Peoples R China
[2] Shenyang Univ Technol, Coll Informat Sci & Engn, Shenyang 110023, Peoples R China
[3] Shenyang Jianzhu Univ, Fac Informat & Control Engn, Shenyang 110168, Peoples R China
基金
中国国家自然科学基金;
关键词
microfluidics; micropump; evaporation effect; capillary effect; flow injection; chemiluminescence;
D O I
10.1016/j.talanta.2005.08.021
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The performance of a micropump, operating on evaporation and capillary effects, developed for microfluidic (lab-on-a-chip) systems, was studied employing it as the fluid drive in a microfluidic flow injection (171) system, with chemiluminescence (CL) detection. The micropump featured simple structure, small dimensions, low fabrication cost and stable and adjustable flow-rates during long working periods. Using a micropump with 6.6 cm(2) evaporation area, with the ambient temperature and relative humidity fluctuating within 2 h in the ranges 20-21 degrees C and 30-32%, respectively, an average flow-rate of 3.02 mu L/min was obtained, with a precision better than 1.2% R.S.D. (n = 61). When applied to the microchip FI-CL system using the luminol/hexacyanoferrate/H2O2 reaction, a precision of 1.4% R.S.D. (n = 11) was obtained for luminol at a sampling frequency of 30 h(-1). (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码:1384 / 1389
页数:6
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