Emergence and Diversification of Fly Pigmentation Through Evolution of a Gene Regulatory Module

被引：110

作者：

Arnoult, Laurent ^{[1
]}

Su, Kathy F. Y. ^{[1
]}

Manoel, Diogo ^{[1
]}

Minervino, Caroline ^{[1
]}

Magrina, Justine ^{[1
]}

Gompel, Nicolas ^{[1
]}

Prud'homme, Benjamin ^{[1
]}

机构：

[1] Aix Marseille Univ, CNRS, UMR 7288, Inst Biol Dev Marseille Luminy, F-13288 Marseille 9, France

来源：

SCIENCE | 2013年 / 339卷 / 6126期

关键词：

DROSOPHILA; PATTERNS;

D O I：

10.1126/science.1233749

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The typical pattern of morphological evolution associated with the radiation of a group of related species is the emergence of a novel trait and its subsequent diversification. Yet the genetic mechanisms associated with these two evolutionary steps are poorly characterized. Here, we show that a spot of dark pigment on fly wings emerged from the assembly of a novel gene regulatory module in which a set of pigmentation genes evolved to respond to a common transcriptional regulator determining their spatial distribution. The primitive wing spot pattern subsequently diversified through changes in the expression pattern of this regulator. These results suggest that the genetic changes underlying the emergence and diversification of wing pigmentation patterns are partitioned within genetic networks.

引用

页码：1423 / 1426

页数：4

共 11 条

[1] Bmp4 and morphological variation of beaks in Darwin's finches [J].