Electrospray ionization source geometry for mass spectrometry: past, present, and future

被引：101

作者：

Manisali, I

Chen, DDY

Schneider, BB

机构：

[1] Univ British Columbia, Dept Chem, Vancouver, BC V6T 1Z1, Canada

[2] MDS SCIEX, Concord, ON L4K 4V8, Canada

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2006年 / 25卷 / 03期

关键词：

atmospheric pressure ionization; commercial ion source design; electrospray ionization; ion source; ion source geometry; mass spectrometry;

D O I：

10.1016/j.trac.2005.07.007

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The geometry of an electrospray ion source plays important roles in the processes of analyte desolvation, ionization, transportation, and detection in a mass spectrometer. We provide a brief account of the scientific principles involved in developing an electrospray ion source, and in the various geometries used to improve the sensitivity of mass spectrometry. We also present some popular configurations currently available and outline future trends in this research area. (C) 2005 Elsevier Ltd. All rights reserved.

引用

页码：243 / 256

页数：14

共 139 条

[31] A MICROSCALE ELECTROSPRAY INTERFACE FOR ONLINE, CAPILLARY LIQUID-CHROMATOGRAPHY TANDEM MASS-SPECTROMETRY OF COMPLEX PEPTIDE MIXTURES [J].