Porphyrins conjugated to DNA as CD reporters of the salt-induced B to Z-DNA transition

被引：42

作者：

Balaz, M ^{[1
]}

Li, BC ^{[1
]}

Steinkruger, JD ^{[1
]}

Ellestad, GA ^{[1
]}

Nakanishi, K ^{[1
]}

Berova, N ^{[1
]}

机构：

[1] Columbia Univ, Dept Chem, New York, NY 10027 USA

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2006年 / 4卷 / 10期

关键词：

D O I：

10.1039/b603409h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The porphyrin chromophore incorporated at the 5'-position of an oligonucleotide allows the simultaneous detection of the B- to Z-DNA transition via the porphyrin Soret band circular dichroism exciton couplet signal around 420 nm and the oligonucleotide CD region below 300 nm, at micromolar concentrations.

引用

收藏

页码：1865 / 1867

页数：3

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