Addition of carbon nucleophiles to cyclic N-acyliminium ions in SDS/water

被引：20

作者：

Camilo, NS ^{[1
]}

Pilli, RA ^{[1
]}

机构：

[1] UNICAMP, Inst Quim, BR-13084971 Campinas, SP, Brazil

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 13期

关键词：

N-acyliminium ions; nucleophilic addition; micelles; SDS; water;

D O I：

10.1016/j.tetlet.2004.02.009

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The acid-catalyzed addition of 1,3-dicarbonyl compounds and activated olefins (silyl enol ethers and ethyl vinyl ether) to N-Boc-2-methoxypyrrolidine (1a) and N-Boc-2-methoxypiperidine (1b) in SDS/water medium is described. Good yields of the corresponding 2-substituted N-Boc pyrrolidines were generally observed from la while moderate yields prevailed from 1b. (C) 2004 Published by Elsevier Ltd.

引用

页码：2821 / 2823

页数：3

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