Does Bone Cement In Percutaneous Vertebroplasty Act as a Stress Riser?

被引:66
作者
Aquarius, Rene [1 ]
van der Zijden, Astrid Maria [1 ]
Homminga, Jasper [2 ]
Verdonschot, Nico [1 ,2 ]
Tanck, Esther [1 ]
机构
[1] Radboud Univ Nijmegen, Med Ctr, Orthopaed Res Lab, NL-6525 ED Nijmegen, Netherlands
[2] Univ Twente, Lab Biomech Engn, NL-7500 AE Enschede, Netherlands
关键词
spine; osteoporosis; vertebral fractures; wedge fractures; fracture cascade; percutaneous vertebroplasty; stress peaks; adjacent-level fractures; VERTEBRAL COMPRESSION FRACTURES; INTERVERTEBRAL DISC; RANDOMIZED-TRIAL; AUGMENTATION; KYPHOPLASTY; OUTCOMES; VOLUME;
D O I
10.1097/01.brs.0000435029.88434.97
中图分类号
R74 [神经病学与精神病学];
学科分类号
100204 [神经病学];
摘要
Study Design. An in vitro cadaveric study. Objective. To determine whether percutaneous vertebroplasty (PVP) with a clinically relevant amount of bone cement is capable of causing stress peaks in adjacent-level vertebrae. Summary of Background Data. It is often suggested that PVP of a primary spinal fracture causes stress peaks in adjacent vertebrae, thereby leading to additional fractures. The in vitro studies that demonstrated this relationship, however, use bigger volumes of bone cement used clinically. Methods. Ten fresh-frozen vertebrae were loaded until failure, while registering force and displacement as well as the pressure under the lower endplate. After failure, the vertebrae were augmented with clinically relevant amounts of bone cement and then again loaded until failure. The force, displacement, and pressure under the lower endplate were again registered. Results. Stress peaks were not related to the location of the injected bone cement. Both failure load and stiffness were significantly lower after augmentation. Conclusion. On the basis of our findings, we conclude that vertebral augmentation with clinically relevant amounts of bone cement does not lead to stress peaks under the endplate. It is therefore unlikely that PVP, in itself, causes detrimental stresses in the adjacent vertebrae, leading to new vertebral fractures.
引用
收藏
页码:2092 / 2097
页数:6
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