Supramolecular helical porphyrin arrays using DNA as a scaffold

被引：38

作者：

Bouamaied, Imenne ^{[1
]}

Nguyen, ThaoNguyen ^{[1
]}

Ruehl, Thomas ^{[1
]}

Stulz, Eugen ^{[1
]}

机构：

[1] Univ Southampton, Sch Chem, Southampton SO17 1BJ, Hants, England

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2008年 / 6卷 / 21期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1039/b813584c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A diphenyl porphyrin substituted nucleotide was incorporated site specifically into DNA, leading to helical stacked porphyrin arrays in the major groove of the duplexes. The porphyrins show an electronic interaction which is significantly enhanced compared to the analogous tetraphenyl porphyrin (TPP) as shown in the large exciton coupling of the porphyrin B-band absorbance. Analogous to the TPP DNA, an induced helical secondary structure is observed in the single strand porphyrin-DNA. The modified DNA can be hybridised to an immobilised complementary strand leading to fluorescent beads.

引用

页码：3888 / 3891

页数：4

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