Achiral benzophenone ligand for highly enantioselective Ru catalysts in ketone hydrogenation

被引：52

作者：

Mikami, K ^{[1
]}

Wakabayashi, K ^{[1
]}

Aikawa, K ^{[1
]}

机构：

[1] Tokyo Inst Technol, Dept Appl Chem, Tokyo 1528552, Japan

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 08期

关键词：

D O I：

10.1021/ol052936o

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The chirality of an "achiral" benzophenone-based complex can be controlled. The benzophenone-based complex thus controlled affords high enantioselectivity in the catalytic asymmetric ketone hydrogenation (up to 99% ee, > 99% yield).

引用

页码：1517 / 1519

页数：3

共 37 条

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