Metabolites from the endophytic fungus Xylaria sp PSU-D14

被引：71

作者：

Pongcharoen, Wipapan ^{[1
]}

Rukachaisirikul, Vatcharin ^{[1
]}

Phongpaichit, Souwalak ^{[2
]}

Kuehn, Till ^{[3
]}

Pelzing, Matthias ^{[4
]}

Sakayaroj, Jariya ^{[5
]}

Taylor, Walter C. ^{[6
]}

机构：

[1] Prince Songkla Univ, Fac Sci, Dept Chem, Songkhla 90112, Thailand

[2] Prince Songkla Univ, Fac Sci, Dept Microbiol, Songkhla 90112, Thailand

[3] Broker Biospin AG, CH-8117 Fallanden, Switzerland

[4] Bruker Biosci, Melbourne, Vic 3010, Australia

[5] Natl Ctr Genet Engn & Biotechnol, Pathum Thani 12120, Thailand

[6] Univ Sydney, Sch Chem, Sydney, NSW 2006, Australia

来源：

PHYTOCHEMISTRY | 2008年 / 69卷 / 09期

关键词：

Xylaria sp; glucosides; sordaricin; benzopyranones;

D O I：

10.1016/j.phytochem.2008.04.003

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Glucoside derivatives, xylarosides A (1) and B (2), were isolated from the broth extract of the endophytic fungus Xylaria sp. PSU-D14 along with two known compounds, sordaricin (3) and 2,3-dihydro-5-hydroxy-2-methyl-4H-1-benzopyran-4-one (4). The structures were assigned by spectroscopic methods. Sordaricin (3), one of the known metabolites, exhibited moderate antifungal activity against Candida albicans ATCC90028 with a MIC value of 32 mu g/ml. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：1900 / 1902

页数：3

共 13 条

[1]

Multiplolides A and B, new antifungal 10-membered lactones from Xylaria multiplex [J].