Monte Carlo simulation of RapidArc radiotherapy delivery

被引:68
作者
Bush, K. [1 ]
Townson, R. [1 ]
Zavgorodni, S. [1 ,2 ]
机构
[1] Univ Victoria, Dept Phys & Astron, Victoria, BC V8W 3P6, Canada
[2] Vancouver Isl Ctr, BC Canc Agcy, Dept Med Phys, Victoria, BC V8R 6V5, Canada
关键词
D O I
10.1088/0031-9155/53/19/N01
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
RapidArc radiotherapy technology from Varian Medical Systems is one of the most complex delivery systems currently available, and achieves an entire intensity-modulated radiation therapy (IMRT) treatment in a single gantry rotation about the patient. Three dynamic parameters can be continuously varied to create IMRT dose distributions-the speed of rotation, beam shaping aperture and delivery dose rate. Modeling of RapidArc technology was incorporated within the existing Vancouver Island Monte Carlo (VIMC) system (Zavgorodni et al 2007 Radiother. Oncol. 84 S49, 2008 Proc. 16th Int. Conf. on Medical Physics). This process was named VIMC-Arc and has become an efficient framework for the verification of RapidArc treatment plans. VIMC-Arc is a fully automated system that constructs the Monte Carlo ( MC) beam and patient models from a standard RapidArc DICOM dataset, simulates radiation transport, collects the resulting dose and converts the dose into DICOM format for import back into the treatment planning system (TPS). VIMC-Arc accommodates multiple arc IMRT deliveries and models gantry rotation as a series of segments with dynamic MLC motion within each segment. Several verification RapidArc plans were generated by the Eclipse TPS on a water-equivalent cylindrical phantom and re-calculated using VIMC-Arc. This includes one 'typical' RapidArc plan, one plan for dual arc treatment and one plan with 'avoidance' sectors. One RapidArc plan was also calculated on a DICOM patient CT dataset. Statistical uncertainty of MC simulations was kept within 1%. VIMC-Arc produced dose distributions that matched very closely to those calculated by the anisotropic analytical algorithm (AAA) that is used in Eclipse. All plans also demonstrated better than 1% agreement of the dose at the isocenter. This demonstrates the capabilities of our new MC system to model all dosimetric features required for RapidArc dose calculations.
引用
收藏
页码:N359 / N370
页数:12
相关论文
共 30 条
[21]   A DICOM-RT-based toolbox for the evaluation and verification of radiotherapy plans [J].
Spezi, E ;
Lewis, DG ;
Smith, CW .
PHYSICS IN MEDICINE AND BIOLOGY, 2002, 47 (23) :4223-4232
[22]   Implementation of random set-up errors in Monte Carlo calculated dynamic IMRT treatment plans [J].
Stapleton, S ;
Zavgorodni, S ;
Popescu, IA ;
Beckham, WA .
PHYSICS IN MEDICINE AND BIOLOGY, 2005, 50 (03) :429-439
[23]   Monte Carlo simulation of helical tomotherapy with PENELOPE [J].
Sterpin, E. ;
Salvat, F. ;
Cravens, R. ;
Ruchala, K. ;
Olivera, G. H. ;
Vynckier, S. .
PHYSICS IN MEDICINE AND BIOLOGY, 2008, 53 (08) :2161-2180
[25]   Coordinate transformations for BEAM/EGSnrc Monte Carlo dose calculations of non-coplanar fields received from a DICOM-compliant treatment planning system [J].
Thebaut, J. ;
Zavgorodni, S. .
PHYSICS IN MEDICINE AND BIOLOGY, 2006, 51 (23) :N441-N449
[26]   Evaluation of uncertainty-based stopping criteria for Monte Carlo calculations of intensity-modulated radiotherapy and arc therapy patient dose distributions [J].
Vanderstraeten, Barbara ;
Olteanu, Ana Maria Luiza ;
Reynaert, Nick ;
Leal, Antonio ;
De Neve, Wilfried ;
Thierens, Hubert .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2007, 69 (02) :628-637
[27]  
WALTERS BRB, 2006, DOSXYZNRC USERS MANU
[28]   INTENSITY-MODULATED ARC THERAPY WITH DYNAMIC MULTILEAF COLLIMATION - AN ALTERNATIVE TO TOMOTHERAPY [J].
YU, CX .
PHYSICS IN MEDICINE AND BIOLOGY, 1995, 40 (09) :1435-1449
[29]  
Zavgorodni S, 2007, RADIOTHER ONCOL, V84, pS49
[30]  
ZAVGORODNI S, 2008, P 16 INT C MED PHYS, P78