A one-pot method for the synthesis of 2-aminobenzimidazoles and related heterocycles

被引：65

作者：

Cee, Victor J. ^{[1
]}

Downing, Nicholas S. ^{[1
]}

机构：

[1] Amgen Inc, Chem Res & Discovery, Cambridge, MA 02139 USA

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 22期

关键词：

aminobenzimidazole; cyclodesulfurization; polymer-supported carbodiimide;

D O I：

10.1016/j.tetlet.2006.03.112

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A rapid and efficient one-pot method for the synthesis of 2-aminobenzimidazoles and related heterocycles is described. The reaction is mediated by a polymer-supported carbodiimide, which simplifies product isolation. The scope and limitations of this method are described. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：3747 / 3750

页数：4

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