Microfluidic high gradient magnetic cell separation

被引：99

作者：

Inglis, DW ^{[1
]}

Riehn, R

Sturm, JC

Austin, RH

机构：

[1] Princeton Univ, PRISM, Princeton Inst Sci & Technol Mat, Princeton, NJ 08544 USA

[2] Princeton Univ, Dept Phys, Princeton, NJ 08544 USA

来源：

JOURNAL OF APPLIED PHYSICS | 2006年 / 99卷 / 08期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1063/1.2165782

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

Separation of blood cells by native susceptibility and by the selective attachment of magnetic beads has recently been demonstrated on microfluidic devices. We discuss the basic principles of how forces are generated via the magnetic susceptibility of an object and how microfluidics can be combined with micron-scale magnetic field gradients to greatly enhance in principle the fractionating power of magnetic fields. We discuss our efforts and those of others to build practical microfluidic devices for the magnetic separation of blood cells. We also discuss our attempts to integrate magnetic separation with other microfluidic features for developing handheld medical diagnostic tools. (C) 2006 American Institute of Physics.

引用

页数：3

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