Switchable Antimicrobial and Antifouling Hydrogels with Enhanced Mechanical Properties

被引：136

作者：

Cao, Bin ^{[1
]}

Tang, Qiong ^{[1
]}

Li, Linlin ^{[2
]}

Humble, Jayson ^{[1
]}

Wu, Haiyan ^{[1
]}

Liu, Lingyun ^{[1
]}

Cheng, Gang ^{[1
]}

机构：

[1] Univ Akron, Dept Chem & Biomol Engn, Akron, OH 44325 USA

[2] Univ Akron, Dept Chem, Akron, OH 44325 USA

来源：

ADVANCED HEALTHCARE MATERIALS | 2013年 / 2卷 / 08期

基金：

美国国家科学基金会;

关键词：

hydrogel; antifouling; zwitterionic materials; antimicrobial; lactone; SELF-ASSEMBLED MONOLAYERS; ZWITTERIONIC HYDROGELS; BACTERIAL BIOFILMS; DRUG-DELIVERY; SURFACE; POLY(CARBOXYBETAINE); SULFOBETAINE; ADSORPTION; RESISTANCE; POLYMERS;

D O I：

10.1002/adhm.201200359

中图分类号：

R318 [生物医学工程];

学科分类号：

100103 [病原生物学];

摘要：

New switchable hydrogels are developed. Under acidic conditions, hydrogels undergo self-cyclization and can catch and kill bacteria. Under neutral/basic conditions, hydrogels undergo ring-opening and can release killed bacterial cells and resist protein adsorption and bacterial attachment. Smart hydrogels also show a dramatically improved mechanical property, which is highly desired for biomedical applications. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：1096 / 1102

页数：7

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