Virogenomics: the virus-host interaction revisited

被引：6

作者：

Andeweg, Arno C. ^{[1
]}

Haagmans, Bart L. ^{[1
]}

Osterhaus, Albert D. M. E. ^{[1
]}

机构：

[1] Erasmus MC, Dept Virol, Rotterdam, Netherlands

来源：

CURRENT OPINION IN MICROBIOLOGY | 2008年 / 11卷 / 05期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/j.mib.2008.09.010

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Genomics tools allow us to assess gene expression 'genome wide' providing an unprecedented view on the host-side of the virus-host interaction. The success of the application of these tools crucially depends on our ability to reduce the total information load while increasing the information density of the data collected. In addition to the advanced data analysis algorithms, gene an notation-pathway databases, and theoretical models, specifically designed sets of complementary experiments are crucial in translating the collected genomics data into palatable knowledge. A better understanding of the molecular basis of virus-host interactions will support the rational design of improved and novel intervention strategies for viral infections.

引用

收藏

页码：461 / 466

页数：6

相关论文

共 38 条

[21] Differential gene regulation by Epstein-Barr virus type 1 and type 2 EBNA2 [J].

Lucchesi, Walter ;

Brady, Gareth ;

Dittrich-Breiholz, Oliver ;

Kracht, Michael ;

Russ, Rainer ;

Farrell, Paul J. .

JOURNAL OF VIROLOGY, 2008, 82 (15) :7456-7466

[22] Distinct gene subsets are induced at different time points after human respiratory syncytial virus infection of A549 cells [J].

Martinez, Isidoro ;

Lombardia, Luis ;

Garcia-Barreno, Blanca ;

Dominguez, Orlando ;

Melero, Jose A. .

JOURNAL OF GENERAL VIROLOGY, 2007, 88 :570-581

[23] Herpes simplex virus triggers and then disarms a host antiviral response [J].

Mossman, KL ;

Macgregor, PF ;

Rozmus, JJ ;

Goryachev, AB ;

Edwards, AM ;

Smiley, JR .

JOURNAL OF VIROLOGY, 2001, 75 (02) :750-758

[24] Identification of an NF-κB-dependent gene network in cells infected by mammalian reovirus [J].

O'Donnell, SM ;

Holm, GH ;

Pierce, JM ;

Tian, B ;

Watson, MJ ;

Chari, RS ;

Ballard, DW ;

Brasier, AR ;

Dermody, TS .

JOURNAL OF VIROLOGY, 2006, 80 (03) :1077-1086

[25] Independent and cooperative antiviral actions of beta interferon and gamma interferon against herpes simplex virus replication in primary human fibroblasts [J].

Peng, Tao ;

Zhu, Jia ;

Hwangbo, Yon ;

Corey, Lawrence ;

Bumgarner, Roger E. .

JOURNAL OF VIROLOGY, 2008, 82 (04) :1934-1945

[26] Upon viral exposure, myeloid and plasmacytoid dendritic cells produce 3 waves of distinct chemokines to recruit immune effectors [J].

Piqueras, B ;

Connolly, J ;

Freitas, H ;

Palucka, AK ;

Banchereau, J .

BLOOD, 2006, 107 (07) :2613-2618

[27] Measles virus induces cell-type specific changes in gene expression [J].

Sato, Hiroki ;

Honma, Reiko ;

Yoneda, Misako ;

Miura, Ryuichi ;

Tsukiyama-Kohara, Kyoko ;

Ikeda, Fusako ;

Seki, Takahiro ;

Watanabe, Shinya ;

Kai, Chieko .

VIROLOGY, 2008, 375 (02) :321-330

[28] QUANTITATIVE MONITORING OF GENE-EXPRESSION PATTERNS WITH A COMPLEMENTARY-DNA MICROARRAY [J].

SCHENA, M ;

SHALON, D ;

DAVIS, RW ;

BROWN, PO .

SCIENCE, 1995, 270 (5235) :467-470

[29] DAVID Knowledgebase: a gene-centered database integrating heterogeneous gene annotation resources to facilitate high-throughput gene functional analysis [J].

Sherman, Brad T. ;

Huang, Da Wei ;

Tan, Qina ;

Guo, Yongjian ;

Bour, Stephan ;

Liu, David ;

Stephens, Robert ;

Baseler, Michael W. ;

Lane, H. Clifford ;

Lempicki, Richard A. .

BMC BIOINFORMATICS, 2007, 8 (1)

[30] The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements [J].

Shi, Leming ;

Reid, Laura H. ;

Jones, Wendell D. ;

Shippy, Richard ;

Warrington, Janet A. ;

Baker, Shawn C. ;

Collins, Patrick J. ;

de Longueville, Francoise ;

Kawasaki, Ernest S. ;

Lee, Kathleen Y. ;

Luo, Yuling ;

Sun, Yongming Andrew ;

Willey, James C. ;

Setterquist, Robert A. ;

Fischer, Gavin M. ;

Tong, Weida ;

Dragan, Yvonne P. ;

Dix, David J. ;

Frueh, Felix W. ;

Goodsaid, Federico M. ;

Herman, Damir ;

Jensen, Roderick V. ;

Johnson, Charles D. ;

Lobenhofer, Edward K. ;

Puri, Raj K. ;

Scherf, Uwe ;

Thierry-Mieg, Jean ;

Wang, Charles ;

Wilson, Mike ;

Wolber, Paul K. ;

Zhang, Lu ;

Amur, Shashi ;

Bao, Wenjun ;

Barbacioru, Catalin C. ;

Lucas, Anne Bergstrom ;

Bertholet, Vincent ;

Boysen, Cecilie ;

Bromley, Bud ;

Brown, Donna ;

Brunner, Alan ;

Canales, Roger ;

Cao, Xiaoxi Megan ;

Cebula, Thomas A. ;

Chen, James J. ;

Cheng, Jing ;

Chu, Tzu-Ming ;

Chudin, Eugene ;

Corson, John ;

Corton, J. Christopher ;

Croner, Lisa J. .

NATURE BIOTECHNOLOGY, 2006, 24 (09) :1151-1161

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