Enantioselective copper-catalyzed conjugate addition and allylic substitution reactions

被引：843

作者：

Alexakis, A. ^{[2
]}

Backvall, J. E. ^{[3
]}

Krause, N. ^{[4
]}

Pamies, O. ^{[1
]}

Dieguez, M. ^{[1
]}

机构：

[1] Univ Rovira & Virgili, Dept Quim Fis & Inorgan, Tarragona 43007, Spain

[2] Univ Geneva, Dept Organ Chem, CH-1211 Geneva 4, Switzerland

[3] Stockholm Univ, Dept Organ Chem, Arrhenius Lab, S-10691 Stockholm, Sweden

[4] Dortmund Univ Technol, D-44227 Dortmund, Germany

来源：

CHEMICAL REVIEWS | 2008年 / 108卷 / 08期

基金：

新加坡国家研究基金会; 瑞典研究理事会;

关键词：

D O I：

10.1021/cr0683515

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The enantioselective copper-catalyzed conjugate additions and allylic substitution reactions, which are used for the formation of new stereogenic C-C bonds, have been presented. The development of highly efficient new copper catalytic systems are obtained by exploring several ligand types, copper sources, and reaction conditions. Efforts to enlarge the scope of the substrates and nucleophiles are also made to increase the potential of their use in the synthesis of more complex chiral organic molecules.

引用

页码：2796 / 2823

页数：28

共 285 条

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