(+)-camphor-derived tri- and tetradentate amino alcohols; synthesis and application as ligands in the nickel catalyzed enantioselective conjugate addition of diethylzinc

被引：60

作者：

deVries, AHM ^{[1
]}

Imbos, R ^{[1
]}

Feringa, BL ^{[1
]}

机构：

[1] UNIV GRONINGEN,GRONINGEN CTR CATALYSIS & SYNTH,DEPT ORGAN & MOL INORGAN CHEM,NL-9747 AG GRONINGEN,NETHERLANDS

来源：

TETRAHEDRON-ASYMMETRY | 1997年 / 8卷 / 09期

关键词：

D O I：

10.1016/S0957-4166(97)00145-6

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Several novel tri- and tetradentate amino alcohol ligands, all derived from (+)-camphor, have been synthesized by using specific N-alkylation procedures. The amino alcohols were employed as chiral ligands in the nickel catalyzed conjugate additions of diethylzine to chalcone and cyclohexenone as model substrates. For the acyclic enone enantioselectivities up to 83% were achieved. (C) 1997 Elsevier Science Ltd.

引用

页码：1467 / 1473

页数：7

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