Isolation and expression analysis of foxi1 and foxi1.2 in zebrafish embryos

被引：23

作者：

Aamar, Emil ^{[1
]}

Dawid, Igor B. ^{[1
]}

机构：

[1] NICHHD, Mol Genet Lab, NIH, Bethesda, MD 20892 USA

来源：

INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY | 2008年 / 52卷 / 07期

基金：

美国国家卫生研究院;

关键词：

Foxj1; Foxj1.2; dorsal forerunner cell; Kupffer's vesicle; floor plate; pronephric duct;

D O I：

10.1387/ijdb.072477ea

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In this report, we present the isolation and identification of a zebrafish homolog of the winged helix\forkhead transcription factor Foxj1. Foxj1 was identified in other species but not in zebrafish. Foxj1 was shown in mice to be required in ciliogenesis and left-right asymmetry establishment. Here we present a spatio-temporal expression pattern of zebrafish foxj1, showing that this gene is expressed in dorsal forerunner cells, Kupffer's vesicle, the floor plate, pronephric ducts and kidney. This expression pattern is overlapping but different from that of the foxj1.2, the closest related gene in zebrafish. Foxj1 in zebrafish appears to have similar functions as those reported in other species connected to ciliogenesis and left-right asymmetry.

引用

页码：985 / 991

页数：7

共 38 条

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