Selective reduction of aromatic azides with hexamethyldisilathiane:: synthesis of new 2-azidopyrrolo[2,1-c][1,4]benzodiazepines

被引：18

作者：

Kamal, A ^{[1
]}

Reddy, KL ^{[1
]}

Reddy, GSK ^{[1
]}

Reddy, BSN ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 17期

关键词：

pyrrolobenzodiazepines; reductive cyclization; antitumour agents;

D O I：

10.1016/j.tetlet.2004.02.148

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Azidopyrrolobenzodiazepines have been synthesized via cyclization of omega-azidocarbonyl compounds employing hexamethyldisilathiane by selectively reducing the aryl azido functionality. (C) 2004 Elsevier Ltd. All right reserved.

引用

页码：3499 / 3501

页数：3

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