Alzheimer's disease may not be a spirochetosis

被引：20

作者：

McLaughlin, R

Kin, NMKNY

Chen, MF

Nair, NPV

Chan, ECS

机构：

[1] McGill Univ, Fac Med, Montreal, PQ H3A 2B4, Canada

[2] Douglas Hosp, Res Ctr, Dept Psychiat, Verdun, PQ H4H 1R4, Canada

[3] McGill Univ, Dept Psychiat, Montreal, PQ H3A 1A1, Canada

来源：

NEUROREPORT | 1999年 / 10卷 / 07期

关键词：

Alzheimer's disease; darkfield microscopy; spirochetes;

D O I：

10.1097/00001756-199905140-00018

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

IT has been reported previously that spirochetes could be one of the causes of Alzheimer's disease (AD). In this study, we have attempted to reproduce these findings by examining fresh blood samples from 22 patients diagnosed with early stage (n = 16) and late stage (n = 6) AD. The patients were participants in a clinical drug trial. Fresh necropsy brain cortical specimens from AD patients (n=7) were also examined. Spirochetes were observed microscopically in the blood of only one late-stage AD patient. None of the brain tissues showed the presence of spirochetes. Our results suggest that spirochetes are probably not associated with AD. NeuroReport 10:1489-1491 (C) 1999 Lippincott WiIliams & Wilkins.

引用

页码：1489 / 1491

页数：3

共 5 条

[1] The Alzheimer family of diseases: Many etiologies, one pathogenesis? [J].