Development of quadrupolar engaging auxiliaries as novel gearing elements for macrocyclization

被引：9

作者：

Collins, SK ^{[1
]}

El-Azizi, Y ^{[1
]}

机构：

[1] Univ Montreal, Dept Chim, Montreal, PQ H3C 3J7, Canada

来源：

PURE AND APPLIED CHEMISTRY | 2006年 / 78卷 / 04期

关键词：

macrocyclization; olefin metathesis; fluoroarenes; quadrupolar; cyclophanes;

D O I：

10.1351/pac200678040783

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The formation of various macrocyclic cyclophanes via ring-closing olefin metathesis is possible through the use of a pendant pentafluorobenzyl ester group. A quadrupolar interaction between the cyclophane core and the auxiliary is proposed to act as a gearing element facilitating cyclization. The development of these noncovalent interactions as gearing elements as well as the investigation of the effect of the site of metathesis upon the macrocyclization process is described.

引用

页码：783 / 789

页数：7

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