Apoptosis detection using magnetic resonance imaging and spectroscopy

被引：31

作者：

Kettunen, MI ^{[1
]}

Brindle, KM ^{[1
]}

机构：

[1] Univ Cambridge, Dept Biochem, Cambridge CB2 1GA, England

来源：

PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY | 2005年 / 47卷 / 3-4期

基金：

英国生物技术与生命科学研究理事会;

关键词：

apoptosis; magnetic resonance imaging; magnetic resonance spectroscopy; contrast agents; molecular imaging;

D O I：

10.1016/j.pnmrs.2005.08.005

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Apoptosis detection using magnetic resonance imaging and spectroscopy is discussed. The applicability for detecting apoptosis in a clinical setting is also discussed. The potential of the methods is compared with other methods such as radionuclide imaging. The process of apoptosis is mediated by increasingly well-defined signaling pathways in the cell. MR spectroscopy is a valuable and now indeed venerable tool for the non-invasive investigation of metabolism in intact cells and tissues.

引用

页码：175 / 185

页数：11

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