Mouse Genome Database (MGD) 2019

被引：505

作者：

Bult, Carol J. ^{[1
]}

Blake, Judith A. ^{[1
]}

Smith, Cynthia L. ^{[1
]}

Kadin, James A. ^{[1
]}

Richardson, Joel E. ^{[1
]}

Anagnostopoulos, A.

Asabor, R.

Baldarelli, R. M.

Beal, J. S.

Bello, S. M.

Blodgett, O.

Butler, N. E.

Christie, K. R.

Corbani, L. E.

Creelman, J.

Dolan, M. E.

Drabkin, H. J.

Giannatto, S. L.

Hale, P.

Hill, D. P.

Law, M.

Mendoza, A.

McAndrews, M.

Miers, D.

Motenko, H.

Ni, L.

Onda, H.

Perry, M.

Recla, J. M.

Richards-Smith, B.

Sitnikov, D.

Tomczuk, M.

Tonorio, G.

Wilming, L.

Zhu, Y.

机构：

[1] Jackson Lab, 600 Main St, Bar Harbor, ME 04609 USA

来源：

NUCLEIC ACIDS RESEARCH | 2019年 / 47卷 / D1期

基金：

美国国家卫生研究院;

关键词：

RESOURCE; BIOLOGY;

D O I：

10.1093/nar/gky1056

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

The Mouse Genome Database (MGD; http://www.informatics.jax.org) is the community model organism genetic and genome resource for the laboratory mouse. MGD is the authoritative source for biological reference data sets related to mouse genes, gene functions, phenotypes, and mouse models of human disease. MGD is the primary outlet for official gene, allele and mouse strain nomenclature based on the guidelines set by the International Committee on Standardized Nomenclature for Mice. In this report we describe significant enhancements to MGD, including two new graphical user interfaces: (i) the Multi Genome Viewer for exploring the genomes of multiple mouse strains and (ii) the Phenotype-Gene Expression matrix which was developed in collaboration with the Gene Expression Database (GXD) and allows researchers to compare gene expression and phenotype annotations for mouse genes. Other recent improvements include enhanced efficiency of our literature curation processes and the incorporation of Transcriptional Start Site (TSS) annotations from RIKEN's FANTOM 5 initiative.

引用

页码：D801 / D806

页数：6

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