The mouse Gene Expression Database (GXD): 2017 update

被引：60

作者：

Finger, Jacqueline H. ^{[1
]}

Smith, Constance M. ^{[1
]}

Hayamizu, Terry F. ^{[1
]}

McCright, Ingeborg J. ^{[1
]}

Xu, Jingxia ^{[1
]}

Law, Meiyee ^{[1
]}

Shaw, David R. ^{[1
]}

Baldarelli, Richard M. ^{[1
]}

Beal, Jon S. ^{[1
]}

Blodgett, Olin ^{[1
]}

Campbell, Jeff W. ^{[1
]}

Corbani, Lori E. ^{[1
]}

Lewis, Jill R. ^{[1
]}

Forthofer, Kim L. ^{[1
]}

Frost, Pete J. ^{[1
]}

Giannatto, Sharon C. ^{[1
]}

Hutchins, Lucie N. ^{[1
]}

Miers, Dave B. ^{[1
]}

Motenko, Howie ^{[1
]}

Stone, Kevin R. ^{[1
]}

Eppig, Janan T. ^{[1
]}

Kadin, James A. ^{[1
]}

Richardson, Joel E. ^{[1
]}

Ringwald, Martin ^{[1
]}

机构：

[1] Jackson Lab, 600 Main St, Bar Harbor, ME 04609 USA

来源：

NUCLEIC ACIDS RESEARCH | 2017年 / 45卷 / D1期

基金：

美国国家卫生研究院;

关键词：

RESOURCE; FEATURES; ATLAS;

D O I：

10.1093/nar/gkw1073

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Gene Expression Database (GXD; www.informatics.jax.org/expression.shtml) is an extensive and well-curated community resource of mouse developmental expression information. Through curation of the scientific literature and by collaborations with large-scale expression projects, GXD collects and integrates data from RNA in situ hybridization, immunohistochemistry, RT-PCR, northern blot and western blot experiments. Expression data from both wild-type and mutant mice are included. The expression data are combined with genetic and phenotypic data in Mouse Genome Informatics (MGI) and made readily accessible to many types of database searches. At present, GXD includes over 1.5 million expression results and more than 300 000 images, all annotated with detailed and standardized metadata. Since our last report in 2014, we have added a large amount of data, we have enhanced data and database infrastructure, and we have implemented many new search and display features. Interface enhancements include: a new Mouse Developmental Anatomy Browser; interactive tissue-by- developmental stage and tissue-by- gene matrix views; capabilities to filter and sort expression data summaries; a batch search utility; gene-based expression overviews; and links to expression data from other species. INTRODUCTION

引用

页码：D730 / D736

页数：7

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