A field guide to foldamers

被引:2220
作者
Hill, DJ
Mio, MJ
Prince, RB
Hughes, TS
Moore, JS [1 ]
机构
[1] Univ Illinois, Beckman Inst Adv Sci & Technol, Dept Chem, Roger Adams Lab, Urbana, IL 61801 USA
[2] Univ Illinois, Beckman Inst Adv Sci & Technol, Dept Mat Sci & Engn, Roger Adams Lab, Urbana, IL 61801 USA
[3] 3M Co, 3M Adhes Technol Ctr, St Paul, MN 55144 USA
[4] Macalester Coll, Dept Chem, St Paul, MN 55105 USA
关键词
D O I
10.1021/cr990120t
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The conformational control in synthetic chain molecules of foldamers were studied. The accumulation of noncovalent interactions that dictated conformation had no direct counterpart in small molecule chemistry. The results showed that the van der Waals and solvophobic interactions were crucial in foldamer designs.
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页码:3893 / 4011
页数:119
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