Real-time phase-resolved functional optical coherence tomography by use of optical Hilbert transformation

被引：83

作者：

Zhao, YH ^{[1
]}

Chen, ZP

Ding, ZH

Ren, HW

Nelson, JS

机构：

[1] Univ Calif Irvine, Beckmen Laser Inst, Irvine, CA 92612 USA

[2] Univ Calif Irvine, Biomed Engn Ctr, Irvine, CA 92612 USA

来源：

OPTICS LETTERS | 2002年 / 27卷 / 02期

关键词：

D O I：

10.1364/OL.27.000098

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We have developed a novel real-time phase-resolved functional optical coherence tomography system that uses optical Hilbert transformation. When we use a resonant scanner in the reference arm of the interferometer, with an axial scanning speed of 4 kHz, the frame rate of both structural and Doppler blood-flow imaging with a size of 100 by 100 pixels is 10 Hz. The system has high sensitivity and a larger dynamic range for measuring the Doppler frequency shift that is due to moving red blood cells. Real-time images of in vivo blood flow in human skin obtained with this interferometer are presented. (C) 2002 Optical Society of America.

引用

页码：98 / 100

页数：3

共 14 条

[1] Optical Doppler tomography [J].

Chen, ZP ;

Zhao, YH ;

Srinivas, SM ;

Nelson, JS ;

Prakash, N ;

Frostig, RD .

IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS, 1999, 5 (04) :1134-1142

[2] Noninvasive imaging of in vivo blood flow velocity using optical Doppler tomography [J].

Chen, ZP ;

Milner, TE ;

Srinivas, S ;

Wang, XJ ;

Malekafzali, A ;

vanGemert, MJC ;

Nelson, JS .

OPTICS LETTERS, 1997, 22 (14) :1119-1121

[3] Optical Doppler tomographic imaging of fluid flow velocity in highly scattering media [J].

Chen, ZP ;

Milner, TE ;

Dave, D ;

Nelson, JS .

OPTICS LETTERS, 1997, 22 (01) :64-66

[4]

Chen ZP, 1998, PHOTOCHEM PHOTOBIOL, V67, P56, DOI 10.1562/0031-8655(1998)067<0056:ODTIVB>2.3.CO

[5]

[6] OPTICAL COHERENCE TOMOGRAPHY [J].

HUANG, D ;

SWANSON, EA ;

LIN, CP ;

SCHUMAN, JS ;

STINSON, WG ;

CHANG, W ;

HEE, MR ;

FLOTTE, T ;

GREGORY, K ;

PULIAFITO, CA ;

FUJIMOTO, JG .

SCIENCE, 1991, 254 (5035) :1178-1181

[7] In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomograghy [J].

Izatt, JA ;

Kulkami, MD ;

Yazdanfar, S ;

Barton, JK ;

Welch, AJ .

OPTICS LETTERS, 1997, 22 (18) :1439-1441

[8] Spectroscopic optical coherence tomography [J].

Morgner, U ;

Drexler, W ;

Kärtner, FX ;

Li, XD ;

Pitris, C ;

Ippen, EP ;

Fujimoto, JG .

OPTICS LETTERS, 2000, 25 (02) :111-113

[9] High-speed fiber-based polarization-sensitive optical coherence tomography of in vivo human skin [J].

Saxer, CE ;

de Boer, JF ;

Park, BH ;

Zhao, YH ;

Chen, ZP ;

Nelson, JS .

OPTICS LETTERS, 2000, 25 (18) :1355-1357

[10] Quantitative differential phase measurement and imaging in transparent and turbid media by optical coherence tomography [J].

Sticker, M ;

Hitzenberger, CK ;

Leitgeb, R ;

Fercher, AF .

OPTICS LETTERS, 2001, 26 (08) :518-520

← 1 2 →