Quantitative differential phase measurement and imaging in transparent and turbid media by optical coherence tomography

被引:102
作者
Sticker, M [1 ]
Hitzenberger, CK [1 ]
Leitgeb, R [1 ]
Fercher, AF [1 ]
机构
[1] Univ Vienna, Inst Med Phys, A-1090 Vienna, Austria
关键词
D O I
10.1364/OL.26.000518
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Differential phase-contrast optical coherence tomography allows one to measure the path-length differences of two transversally separated beams in the nanometer range. We calculate these path-length differences ti-om the phase functions of the interferometric signals. Pure phase objects consisting of chromium layers containing steps of approximately 100-200-nm height were imaged. Phase differences can be measured with a precision of +/-2 degrees, corresponding to a path-difference resolution of 2-3 nm. To investigate the influence of scattering, we imaged the phase objects through scattering layers with increasing scattering coefficients. The limit of phase imaging through these layers was at approximately 8-9 mean free path lengths thick (single pass). (C) 2001 Optical Society of America.
引用
收藏
页码:518 / 520
页数:3
相关论文
共 8 条
[1]   Digital holography for quantitative phase-contrast imaging [J].
Cuche, E ;
Bevilacqua, F ;
Depeursinge, C .
OPTICS LETTERS, 1999, 24 (05) :291-293
[2]   Optical low-coherence reflectometer for differential phase measurement [J].
Davé, DP ;
Milner, TE .
OPTICS LETTERS, 2000, 25 (04) :227-229
[3]   Two-dimensional birefringence imaging in biological tissue by polarization-sensitive optical coherence tomography [J].
deBoer, JF ;
Milner, TE ;
vanGemert, MJC ;
Nelson, JS .
OPTICS LETTERS, 1997, 22 (12) :934-936
[4]   Differential phase contrast in optical coherence tomography [J].
Hitzenberger, CK ;
Fercher, AF .
OPTICS LETTERS, 1999, 24 (09) :622-624
[5]   Differential phase imaging in optical coherence tomography [J].
Hitzenberger, CK ;
Sticker, M ;
Leitgeb, R ;
Sattmann, H ;
Fercher, AF .
COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICAL SCIENCE AND CLINICAL APPLICATIONS IV, 2000, 3915 :90-96
[6]   In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomograghy [J].
Izatt, JA ;
Kulkami, MD ;
Yazdanfar, S ;
Barton, JK ;
Welch, AJ .
OPTICS LETTERS, 1997, 22 (18) :1439-1441
[7]   An optical coherence microscope with enhanced resolving power in thick tissue [J].
Schmitt, JM ;
Lee, SL ;
Yung, KM .
OPTICS COMMUNICATIONS, 1997, 142 (4-6) :203-207
[8]   Phase-resolved optical coherence tomography and optical Doppler tomography for imaging blood flow in human skin with fast scanning speed and high velocity sensitivity [J].
Zhao, YH ;
Chen, ZP ;
Saxer, C ;
Xiang, SH ;
de Boer, JF ;
Nelson, JS .
OPTICS LETTERS, 2000, 25 (02) :114-116