Determination of norfloxacin using a terbium-sensitized electrogenerated chemiluminescence method

被引：23

作者：

Chen, SL

Liu, Y

Zhao, HC ^{[1
]}

Jin, LP

Zhang, ZL

Zheng, YZ

机构：

[1] Beijing Normal Univ, Dept Chem, Beijing 100875, Peoples R China

[2] Acad Sinica, Inst Biophys, Beijing 100101, Peoples R China

来源：

LUMINESCENCE | 2006年 / 21卷 / 01期

关键词：

electrogenerated chemiluminescence; cyclic voltammetry; terbium; norfloxacin (NFLX); sodium sulphite;

D O I：

10.1002/bio.876

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A simple electrogenerated chemiluminescence (ECL) analysis method for the determination of norfloxacin (NFLX) is reported. It is based on ECL produced by Na2SO3, which is sensitized by the Tb-NFLX complex. The relative ECL intensity of the Tb3+-NFLX-Na2SO3 system is proportional to the amount of NFLX. The optimized experimental conditions were investigated. The linear range and detection limit for NFLX were 1.0 x 10(-10)-8.0 X 10(-7) mol/L and 2.8 x 10(-11) mol/L, respectively. This method was successfully applied to the determination of NFLX in a capsule. NFLX in urine can be directly detected without pretreatment or separation. Copyright (C) 2005 John Wiley & Sons, Ltd.

引用

页码：20 / 25

页数：6

共 48 条

[41] Multiresidue determination of (fluoro)quinolone antibiotics in swine kidney using liquid chromatography-tandem mass spectrometry [J].