Toll-like receptors and graft rejection

被引：11

作者：

Liu, Guangwei

Wu, You

Gong, Shouliang

Zhao, Yong

机构：

[1] Chinese Acad Sci, Inst Zool, State Key Lab Biomembrane & Membrane Biotechnol, Transplantat Biol Res Div, Beijing 100080, Peoples R China

[2] Jilin Univ, Sch Publ Hlth, Minist Hlth Radiobiol Res Unit, Changchun 130023, Peoples R China

来源：

TRANSPLANT IMMUNOLOGY | 2006年 / 16卷 / 01期

关键词：

Toll-like receptors; organ transplantation; graft rejection; innate immunity;

D O I：

10.1016/j.trim.2006.03.006

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Innate immunity plays a role in fighting against invading microorganisms. Emerging evidence suggests that in addition to responding to pathogen-associated molecular patterns of microorganisms, Toll-like receptors (TLRs) can be activated by endogenous ligands expressed by mammalian cells. Clinical and laboratory studies have shown that TLRs may participate in organ graft rejection and transplant immune tolerance, which are briefly reviewed in the present manuscript. (C) 2006 Elsevier B.V. All rights reserved.

引用

页码：25 / 31

页数：7

共 69 条

[41] The Toll-IL-1 receptor adaptor family grows to five members [J].

O'Neill, LAJ ;

Fitzgerald, KA ;

Bowie, AG .

TRENDS IN IMMUNOLOGY, 2003, 24 (06) :287-290

[42] Heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex [J].

Ohashi, K ;

Burkart, V ;

Flohé, S ;

Kolb, H .

JOURNAL OF IMMUNOLOGY, 2000, 164 (02) :558-561

[43] TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-β induction [J].

Oshiumi, H ;

Matsumoto, M ;

Funami, K ;

Akazawa, T ;

Seya, T .

NATURE IMMUNOLOGY, 2003, 4 (02) :161-167

[44] Innate immunity influences long-term outcomes after human lung transplant [J].

Palmer, SM ;

Burch, LH ;

Trindade, AJ ;

Davis, RD ;

Herczyk, WF ;

Reinsmoen, NL ;

Schwartz, DA .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2005, 171 (07) :780-785

[45] Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation [J].

Palumbo, R ;

Sampaolesi, M ;

De Marchis, F ;

Tonlorenzi, R ;

Colombetti, S ;

Mondino, A ;

Cossu, G ;

Bianchi, ME .

JOURNAL OF CELL BIOLOGY, 2004, 164 (03) :441-449

[46] Injury primes the innate immune system for enhanced toll-like receptor reactivity [J].

Paterson, HM ;

Murphy, TJ ;

Purcell, EJ ;

Shelley, O ;

Kriynovich, SJ ;

Lien, E ;

Mannick, JA ;

Lederer, JA .

JOURNAL OF IMMUNOLOGY, 2003, 171 (03) :1473-1483

[47] Toll-like, receptor 8-mediated reversal of CD4+ regulatory T cell function [J].

Peng, GY ;

Guo, Z ;

Kiniwa, Y ;

Voo, KS ;

Peng, WY ;

Fu, TH ;

Wang, DY ;

Li, YC ;

Wang, HY ;

Wang, RF .

SCIENCE, 2005, 309 (5739) :1380-1384

[48] Does human leukocyte antigen matching influence the outcome of lung transplantation? An analysis of 3,549 lung transplantations [J].

Quantz, MA ;

Bennett, LE ;

Meyer, DM ;

Novick, RJ .

JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2000, 19 (05) :473-479

[49] Toll-like receptors and surgical disease [J].

Raeburn, CD ;

Calkins, CM ;

Zimmerman, MA ;

Arya, J ;

Barsness, KA ;

Harken, AH .

SURGERY, 2002, 131 (05) :477-483

[50]

Rao EY, 2005, PROG BIOCHEM BIOPHYS, V32, P106

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