A New Synthetic Strategy towards Bioactive Merosesquiterpenoids

被引：6

作者：

Alvarez-Manzaneda, Enrique ^{[1
]}

Chahboun, Rachid ^{[1
]}

Cabrera, Eduardo ^{[1
]}

Alvarez, Esteban ^{[1
]}

Haidour, Ali ^{[1
]}

Miguel Ramos, Jose ^{[1
]}

Alvarez-Manzaneda, Ramon ^{[2
]}

Luis Romera, Juan ^{[1
]}

Angeles Escobar, Mari ^{[1
]}

Messouri, Ibtissam ^{[1
]}

机构：

[1] Univ Granada, Fac Ciencias, Inst Biotechnol, Dept Quim Organ, E-18071 Granada, Spain

[2] Univ Almeria, Fac Ciencias, Dept Quim Organ, Almeria, Spain

来源：

SYNTHESIS-STUTTGART | 2008年 / 24期

关键词：

Diels-Alder reactions; esters; natural products; quinones; terpenoids;

D O I：

10.1055/s-0028-1083238

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

The Diels-Alder cycloaddition of the labdane diene methyl trans-communate with various representative dienophiles has been studied. Based on this, a novel strategy for synthesizing bioactive merosesquiterpenes is reported. This methodology affords considerable atom and step economy and makes it feasible to prepare A-ring functionalised compounds. A study on the synthesis of the fungitoxic pycnanthuquinone C has been carried out.

引用

页码：4019 / 4027

页数：9

共 31 条

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