Synthesis of C13-C22 fragment of the marine sponged polyketide callystatin A

被引：25

作者：

Dias, LC ^{[1
]}

Meira, PRR ^{[1
]}

机构：

[1] Univ Estadual Campinas, Inst Quim, BR-13083970 Campinas, SP, Brazil

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 02期

基金：

巴西圣保罗研究基金会;

关键词：

D O I：

10.1016/S0040-4039(01)02104-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We wish to report here our initial efforts towards the total synthesis of callystatin A, describing the synthesis of the C13-C22 fragment. This asymmetric approach uses an efficient syn-aldol reaction, and a diastereoselective epoxidation of an allylic alcohol with m-CPBA followed by epoxide opening with Me2CuLi. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：185 / 187

页数：3

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