Oestrogen receptor β:: what it means for patients with breast cancer

被引：106

作者：

Speirs, V

Carder, PJ

Lane, S

Dodwell, D

Lansdown, MR

Hanby, AM

机构：

[1] Univ Leeds, Mol Med Unit, Leeds, W Yorkshire, England

[2] Univ Leeds, Acad Unit Pathol, Leeds, W Yorkshire, England

[3] Leeds Teaching Hosp NHS Trust, Breast Unit, Leeds, W Yorkshire, England

来源：

LANCET ONCOLOGY | 2004年 / 5卷 / 03期

关键词：

D O I：

10.1016/S1470-2045(04)01413-5

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Oestrogen receptor (ER) a is a well established prognostic marker in breast cancer, and all patients who are ERalpha positive receive tamoxifen as adjuvant endocrine therapy. Although ERalpha predicts a favourable disease outcome, the usefulness of ERbeta as a clinical prognostic marker remains to be defined. Here, we outline the history of both ERs and discuss the implications ERbeta has to patients with breast cancer.

引用

收藏

页码：174 / 181

页数：10

相关论文

共 81 条

[31]

Kurebayashi J, 2000, CLIN CANCER RES, V6, P512

[32] ERβ inhibits proliferation and invasion of breast cancer cells [J].

Lazennec, G ;

Bresson, D ;

Lucas, A ;

Chauveau, C ;

Vignon, F .

ENDOCRINOLOGY, 2001, 142 (09) :4120-4130

[33] Immunohistochemical detection of steroid receptors in breast cancer: a working protocol [J].

Leake, R ;

Barnes, D ;

Pinder, S ;

Ellis, I ;

Anderson, L ;

Anderson, T ;

Adamson, R ;

Rhodes, T ;

Miller, I ;

Walker, R .

JOURNAL OF CLINICAL PATHOLOGY, 2000, 53 (08) :634-635

[34] Estrogen receptor β -: Potential functional significance of a variety of mRNA isoforms [J].

Lewandowski, S ;

Kalita, K ;

Kaczmarek, L .

FEBS LETTERS, 2002, 524 (1-3) :1-5

[35]

Leygue E, 1999, CANCER RES, V59, P1175

[36]

Leygue E, 1998, CANCER RES, V58, P3197

[37] Estrogen receptor beta expression in invasive breast cancer [J].

Mann, S ;

Laucirica, R ;

Carlson, N ;

Younes, PS ;

Ali, N ;

Younes, A ;

Li, Y ;

Younes, M .

HUMAN PATHOLOGY, 2001, 32 (01) :113-118

[38] LOCALIZATION OF THE ESTROGEN-RECEPTOR LOCUS (ESR) TO CHROMOSOME 6Q25.1 BY FISH AND A SIMPLE POST-FISH BANDING TECHNIQUE [J].

MENASCE, LP ;

WHITE, GRM ;

HARRISON, CJ ;

BOYLE, JM .

GENOMICS, 1993, 17 (01) :263-265

[39] Clinicopathological characteristics of estrogen receptor-β-positive human breast cancers [J].

Miyoshi, Y ;

Taguchi, T ;

Gustafsson, JÅ ;

Noguchi, S .

JAPANESE JOURNAL OF CANCER RESEARCH, 2001, 92 (10) :1057-1061

[40] Cloning and characterization of human estrogen receptor β isoforms [J].

Moore, JT ;

McKee, DD ;

Slentz-Kesler, K ;

Moore, LB ;

Jones, SA ;

Horne, EL ;

Su, JL ;

Kliewer, SA ;

Lehmann, JM ;

Willson, TM .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1998, 247 (01) :75-78

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