Chromatin, transcript elongation and alternative splicing

被引：128

作者：

Kornblihtt, AR

机构：

[1] Univ Buenos Aires, Fac Ciencias Exactas & Nat, Dept Fisiol & Biol Mol, LFBM, RA-1428 Buenos Aires, DF, Argentina

[2] Univ Buenos Aires, Fac Ciencias Exactas & Nat, IFIByNE, CONICET, RA-1428 Buenos Aires, DF, Argentina

来源：

NATURE STRUCTURAL & MOLECULAR BIOLOGY | 2006年 / 13卷 / 01期

关键词：

D O I：

10.1038/nsmb0106-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A recent study reveals that the chromatin-remodeling factor SWI/SNF regulates alternative splicing by creating internal 'roadblocks' to transcriptional elongation where the phosphorylation status of RNA pol II is qualitatively changed.

引用

页码：5 / 7

页数：3

共 12 条

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