Polarization effects in optical coherence tomography of various biological tissues

被引:81
作者
de Boer, JF [1 ]
Srinivas, SM
Park, BH
Pham, TH
Chen, ZP
Milner, TE
Nelson, JS
机构
[1] Univ Calif Irvine, Beckman Laser Inst & Med Clin, Irvine, CA 92612 USA
[2] Univ Texas, Biomed Engn Program, Austin, TX 78712 USA
关键词
biological tissues; biomedical imaging; birefringence; optical tomography; polarization;
D O I
10.1109/2944.796347
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Polarization sensitive optical coherence tomography (PS-OCT) was used to obtain spatially resolved ex vivo images of polarization changes in skeletal muscle, bone, skin and brain. Through coherent detection of two orthogonal polarization states of the signal formed by interference of light reflected from the biological sample and a mirror in the reference arm of a Michelson interferometer, the depth resolved change in polarization was measured. Inasmuch as any fibrous structure will influence the polarization of light, PS-OCT is a potentially powerful technique investigating tissue structural properties, In addition, the effects of single polarization state detection on OCT image formation is demonstrated.
引用
收藏
页码:1200 / 1204
页数:5
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