Structural and signalling molecules come together at tight junctions

被引：259

作者：

Tsukita, S ^{[1
]}

Furuse, M ^{[1
]}

Itoh, M ^{[1
]}

机构：

[1] Kyoto Univ, Fac Med, Dept Cell Biol, Sakyo Ku, Kyoto 606, Japan

来源：

CURRENT OPINION IN CELL BIOLOGY | 1999年 / 11卷 / 05期

关键词：

D O I：

10.1016/S0955-0674(99)00016-2

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Tight junctions (TJs) have been suggested to act both as barriers and fences, but lack of information on the constituents of TJ strands has hampered the direct assessment of these functions. Over the past year, our understanding of the molecular architecture of TJ strands has increased markedly and we are ready to experimentally examine how TJs are involved in their dual functions.

引用

页码：628 / 633

页数：6

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